Allergic Disease

  • Diagnosis
  • Background
  • Lab Tests
  • References
  • Related Topics

Indications for Testing

  • Concern for specific allergy (eg, hymenoptera)
  • Progressive disease unresponsive to medical therapy (eg, sinusitis, asthma)

Laboratory Testing

  • Blood panel allergen testing
    • Recommended if specific allergen affecting patient is unknown
  • Identification of specific allergens may allow for immunotherapy
    • Use quantitative immunoCAP florescent EIA for IgE – do not use IgA tests
    • Screening test should include a balanced mixture of allergens most commonly associated with inhalant allergies
      • Alternaria alternata
      • Bermuda grass
      • Cat epithelium and dander
      • Common ragweed
      • Dermatophagoides farinae
      • Dog dander
      • Elm tree
      • Kentucky bluegrass
      • Oak tree
      • Penicillium notatum
      • Russian thistle
  • Serum IgE testing has limited usefulness in allergic disease evaluation

Other Testing

  • Skin prick or scratch testing
    • Higher sensitivity than blood tests but requires patients to stop antiallergy medication
    • Not recommended for patients with eczema, poorly controlled asthma
    • False positives in patients with dermographism, urticaria, cutaneous mastocytosis

Differential Diagnosis

Allergic rhinitis, asthma and anaphylaxis as well as sinopulmonary infections may result from inhalant allergens.  Allergen immunotherapy is established as an effective treatment for patients with IgE-mediated reactions to hymenoptera, allergic rhinitis and allergic bronchial asthma.

Epidemiology

  • Incidence – increasing incidence of both atopic and asthma disease over the last 4-5 decades
    • Incidence of rhinitis – 1/500
  • Age – onset usually in childhood
  • Sex – M:F, equal

Risk Factors

  • Genetics – family member with disease increases risk
  • Airborne irritants – smoking, pollution, pollen

Clinical Presentation

  • General malaise, sleep disturbances
  • Sinus/nasal disease
    • Tender and swollen sinuses
    • Pressure in sinus area when leaning forward
    • Frontal headaches
    • Nasal obstruction and discharge
    • Post-nasal drip, rhinitis
    • Rhinorrhea
  • Dermatologic disease
    • Atopic eczema – papular lesions on flexural surfaces
  • Pulmonary disease
    • Wheeze
    • Cough
    • Dyspnea
  • Ophthalmic disease
    • Conjunctivitis
    • Itchy eyes

Drug-related Allergens

Allergen, Drugs, Amoxicillin 0055421
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Drugs, Ampicillin 0055422
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Drugs, Penicillin G (major) 0099628
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Drugs, Penicillin V (minor) 0099629
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Epidermal and Animal Protein Allergens

Allergen, Epidermals and Animal Proteins, Australian Parrot Droppings IgE 0099635
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Epidermals and Animal Proteins, Budgerigar Droppings (Parakeet) 0099714
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Epidermals and Animal Proteins, Cat Dander 0055006
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Epidermals and Animal Proteins, Chicken Feathers 0055378
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Epidermals and Animal Proteins, Cow Hair and Dander 0055044
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Epidermals and Animal Proteins, Dog Dander 0099568
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Epidermals and Animal Proteins, Duck Feathers IgE 2003300
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Epidermals and Animal Proteins, Feather Mix 0055037
Method: Qualitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Epidermals and Animal Proteins, Goat Epithelium IgE 0055188
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Epidermals and Animal Proteins, Goose Feathers 0055177
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Epidermals and Animal Proteins, Guinea Pig Epithelium IgE 0055190
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Epidermals and Animal Proteins, Hamster Epithelium 0055189
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Epidermals and Animal Proteins, Horse Hair and Dander 0055059
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Epidermals and Animal Proteins, Mouse Epithelium 0055191
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Epidermals and Animal Proteins, Mouse Urine IgE 0055192
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Epidermals and Animal Proteins, Parakeet Feathers (Budgerigar) 0055193
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Epidermals and Animal Proteins, Pig (Swine) Epithelium IgE 0055195
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Epidermals and Animal Proteins, Pigeon Stools IgE 0055196
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Epidermals and Animal Proteins, Rabbit Epithelium 0099544
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Epidermals and Animal Proteins, Rat Epithelium IgE 0055197
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Epidermals and Animal Proteins, Rat Urine IgE 0055198
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Epidermals and Animal Proteins, Sheep Epithelium/Wool 0055199
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Fungi/Mold Allergens

Allergen, Fungi and Molds, Alternaria alternata (tenuis) 0055001
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Fungi and Molds, Alternaria tenuis IgG 0097773
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Fungi and Molds, Aspergillus fumigatus 0055061
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Fungi and Molds, Aspergillus fumigatus IgG 2008601
Method: Quantitative Enzyme Immunoassay

Allergen, Fungi and Molds, Aspergillus niger IgE 0092598
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Fungi and Molds, Aureobasidium pullulans 0055383
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Fungi and Molds, Aureobasidium pullulans IgG 0097305
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Fungi and Molds, Bermuda Grass Smut IgE 2010722
Method: Quantitative Enzyme Immunoassay

Allergen, Fungi and Molds, Bipolaris spicifera (Curvularia) IgE 2010836
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Fungi and Molds, Botrytis cinerea IgE 2004670
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Fungi and Molds, Candida albicans 0055004
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Fungi and Molds, Candida albicans IgG 0097304
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Fungi and Molds, Cephalosporium 0098522
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Fungi and Molds, Chaetomium globosum IgE 2007625
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Fungi and Molds, Cladosporium IgG 0097314
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Fungi and Molds, Corn Smut IgE 2010726
Method: Quantitative Enzyme Immunoassay

Allergen, Fungi and Molds, Curvularia lunata 0055377
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Fungi and Molds, Epicoccum 0099599
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Fungi and Molds, Epidermophyton floccosum IgE 2010728
Method: Quantitative Enzyme Immunoassay

Allergen, Fungi and Molds, Fusarium moniliforme 0055376
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Fungi and Molds, Fusarium proliferatum/moniliforme IgG 0093454
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Fungi and Molds, Helminthosporium 0099541
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Fungi and Molds, Helminthosporium halodes/Setomelanomma rostrata IgG 0097313
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Fungi and Molds, Hormodendrum (Cladosporium) 0055038
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Fungi and Molds, Johnson Grass Smut IgE 2010730
Method: Quantitative Enzyme Immunoassay

Allergen, Fungi and Molds, Mucor racemosus 0055442
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Fungi and Molds, Mucor racemosus IgG 0097316
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Fungi and Molds, Oat Smut IgE 2010736
Method: Quantitative Enzyme Immunoassay

Allergen, Fungi and Molds, Penicillium chrysogenum/notatum IgG 0097310
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Fungi and Molds, Penicillium notatum 0055080
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Fungi and Molds, Phoma betae 0055390
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Fungi and Molds, Phoma betae IgG 0097309
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Fungi and Molds, Pityrosporum orbiculare/Malassezia IgE 2006438
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Fungi and Molds, Rhizopus nigricans 0099555
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Fungi and Molds, Rhizopus nigricans IgG 0097307
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Fungi and Molds, Staphylococcal Enterotoxin A IgE 0092590
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Fungi and Molds, Staphylococcal Enterotoxin B IgE 0092588
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Fungi and Molds, Stemphylium botryosum 0050357
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Fungi and Molds, Stemphylium solani IgE 0099551
Method: Quantitative Enzyme Immunoassay

Allergen, Fungi and Molds, Trichoderma viride IgE 2010816
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Fungi and Molds, Trichophyton mentagrophytes, Interdigitale Variant 0050147
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Fungi and Molds, Trichophyton rubrum IgG 0090393
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Fungi and Molds, Wheat Smut IgE 2010744
Method: Quantitative Enzyme Immunoassay

Allergen, Stemphylium herbarum/botryosum, IgG 0097308
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergens, Additional Molds Profile IgE 0051833
Method: ImmunoCAP Fluorescent Enzyme Immunoassay

Grass Allergens

Allergen, Grass, Alfalfa IgE 0099901
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Grass, Bahia 0055151
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Grass, Bent Grass/Redtop Grass 0055057
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Grass, Bermuda 0055070
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Grass, Brome Grass 0099774
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Grass, Canary Grass 0050536
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Grass, Common Reed IgE 0055184
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Grass, Cultivated Barley Pollen IgE 0098644
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Grass, Cultivated Corn Pollen 0098641
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Grass, Cultivated Oat Pollen 0050533
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Grass, Cultivated Wheat Pollen 0098642
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Grass, Johnson Grass 0055047
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Grass, June Grass/Kentucky Bluegrass 0055017
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Grass, Meadow Fescue 0055053
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Grass, Orchard Grass/Cocksfoot 0055052
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Grass, Perennial Rye Grass 0055028
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Grass, Salt Grass IgE 0098470
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Grass, Sweet Vernal Grass 0099667
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Grass, Timothy Grass 0055032
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

House Dust Allergens

Allergen, House Dust Greer 0055091
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, House Dust Stier 0055092
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

IgE

Allergen Panel, IgE by ImmunoCap ISAC 2005894
Method: Semi-Quantitative ImmunoCAP® Solid-phase Allergen Chip

Inhalant Allergens

Allergens, Inhalant Multiallergen IgE, Qualitative 0055368
Method: Qualitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergens, Inhalants Panel 11 IgE 0055113
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergens, Inhalants, California Environmental 0055309
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergens, Inhalants, California Pollen 0055306
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergens, Inhalants, Comprehensive Profile 2 0055231
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergens, Inhalants, Comprehensive Profile IgE 0055312
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergens, Inhalants, Environmental Profile 10 0055305
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergens, Inhalants, Indoor 0051830
Method: ImmunoCAP Fluorescent Enzyme Immunoassay

Allergens, Inhalants, Midwest Comprehensive 1 0055138
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergens, Inhalants, Midwest Comprehensive 2 0055171
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergens, Inhalants, Northeast Comprehensive 0055116
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergens, Inhalants, Profile 13 IgE 0055175
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergens, Inhalants, Profile 18 IgE 0055178
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergens, Inhalants, Profile 28 IgE 2002123
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergens, Inhalants, Southeast Coastal Comprehensive 0055149
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergens, Inhalants, Southern California Profile 0055111
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergens, Inhalants, Southwest Basic 0055043
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergens, Inhalants, Southwest Comprehensive 1 0055360
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergens, Inhalants, Southwest Comprehensive 2 0055367
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergens, Inhalants, Southwest Extended Profile 0055375
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergens, Inhalants, Southwest Valley Profile 0055230
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergens, Inhalants, Western Environmental IgE 2006399
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergens, Inhalants/Foods, Comprehensive Profile 1 0055114
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergens, Inhalants/Foods, Comprehensive Profile 2 0055099
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergens, Inhalants/Foods, Environmental Profile 0055307
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergens, Inhalants/Foods, Pacific Northwest Profile 0055131
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergens, Inhalants/Foods, Profile A 0055126
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergens, Inhalants/Foods, Southeast Profile 0055240
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergens, Inhalants/Foods, Western Allergy Profile 0055129
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Insect/Venom Allergens

Allergen, Insect and Venom, Bumble Bee Venom IgE 2007627
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Insect, Mosquito, IgE 0055210
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Insects and Venom, Cockroach, American 0050151
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Insects and Venom, Cockroach, German 0055088
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Insects and Venom, Fire Ant, Imported 0098272
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Insects and Venom, Honey Bee IgE 0055039
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Insects and Venom, Honey Bee IgG 0055400
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Insects and Venom, Paper Wasp 0055048
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Insects and Venom, Paper Wasp IgG 0055415
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Insects and Venom, White-Faced Hornet 0055046
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Insects and Venom, White-Faced Hornet IgG 0055405
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Insects and Venom, Yellow Hornet IgG 0055420
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Insects and Venom, Yellow Jacket IgG 0055410
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Insects and Venom, Yellow Jacket Venom 0055139
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Insects and Venom, Yellow-Faced Hornet 0055065
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Latex Allergens

Allergens, Latex/Cross-Reactive Food Panel IgE 0055245
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Mite Allergens

Allergen, Mites, Acarus siro IgE 0055009
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Mites, B. tropicalis 2006019
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Mites, D. farinae 0055064
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Mites, D. microceras IgE 0055060
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Mites, D. pteronyssinus 0055063
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Mites, Euroglyphus maynei IgE 0055087
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Mites, Glycyphagus domesticus IgE 0055095
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Mites, Lepidoglyphus destructor 0050143
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Mites, Tyrophagus putrescentiae IgE 0055183
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Occupational Allergens

Allergen, Occupational, Cotton Seed IgE 2006687
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Occupational, Ethylene Oxide IgE 0098421
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Occupational, Formaldehyde IgE 0098423
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Occupational, Isocyanate HDI 0098418
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Occupational, Isocyanate MDI 0098419
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Occupational, Isocyanate TDI 0098420
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Occupational, Latex IgE, Enhanced 0099614
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Occupational, Phthalic Anhydride IgE 0098422
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Occupational, Tobacco 0099548
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Parasite Allergens

Allergen, Parasite, Ascaris 0055213
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Pediatrics

Allergens, Pediatric Allergy, March (Progression) Profile IgE 0050529
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergens, Pediatric Foods/Inhalants Profile 0055300
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergens, Pediatric Inhalants, Southwest 0055365
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergens, Pediatric Profile IgE 0050152
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Respiratory Allergens

Allergens, Respiratory Panel, Region 1, North Atlantic (CT, MA, NJ, PA, VT, ME, NH, NY, RI) IgE 2005717
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergens, Respiratory Panel, Region 10, Southwestern Grasslands (OK, TX) IgE 2006038
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergens, Respiratory Panel, Region 11, Rocky Mountain (AZ, ID, NM, WY CO, MT, UT) IgE 2006039
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergens, Respiratory Panel, Region 12, Arid Southwest (S. AZ, S.E. CA) IgE 2006040
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergens, Respiratory Panel, Region 13, Southern Coastal (CA) IgE 2006041
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergens, Respiratory Panel, Region 14, Central California (CA) IgE 2006042
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergens, Respiratory Panel, Region 15, Intermountain West (NV, S. ID) IgE 2006043
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergens, Respiratory Panel, Region 16, Inland Northwest (OR, Central and East WA) IgE 2006044
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergens, Respiratory Panel, Region 17, Pacific Northwest (NW CA, W. OR, WA) IgE 2006045
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergens, Respiratory Panel, Region 18, Alaska IgE 2006046
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergens, Respiratory Panel, Region 19, Puerto Rico IgE 2006047
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergens, Respiratory Panel, Region 2, Mid-Atlantic (DE, MD, VA, DC, NC) IgE 2005718
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergens, Respiratory Panel, Region 20, Hawaii IgE 2006048
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergens, Respiratory Panel, Region 3, South Atlantic (GA, SC, N. FL) IgE 2006025
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergens, Respiratory Panel, Region 4, Subtropic Florida (S. of Orlando) IgE 2006026
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergens, Respiratory Panel, Region 5, Ohio Valley (IN, OH, TN, WV, KY) IgE 2006031
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergens, Respiratory Panel, Region 6, South Central (AL, AR, LA, MS) IgE 2006032
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergens, Respiratory Panel, Region 7, Northern Midwest (MI, WI, MN) IgE 2006033
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergens, Respiratory Panel, Region 8, Central Midwest (IL, MO, IA) IgE 2006034
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergens, Respiratory Panel, Region 9, Great Plains (KS, NE, ND, SD) IgE 2006037
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergens, Upper Respiratory Disease Profile, Region 9A 0051355
Method: Quantitative ImmunoCAP  Fluorescent Enzyme Immunoassay

Tree Allergens

Allergen, Tree, Acacia Tree 0055141
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Tree, Alder Tree 0099486
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Tree, American Beech Tree 0055153
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Tree, Arizona Cypress IgE 0055150
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Tree, Aspen IgE 2007775
Method: Quantitative Enzyme Immunoassay

Allergen, Tree, Bald Cypress IgE 2007621
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Tree, Bayberry IgE 0098870
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Tree, Birch Tree 0055058
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Tree, Black Locust IgE 0092053
Method: Quantitative Enzyme Immunoassay

Allergen, Tree, Black Willow IgE 2007876
Method: Quantitative Enzyme Immunoassay

Allergen, Tree, Box Elder/Maple Tree 0055003
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Tree, California Pepper IgE 0097794
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Tree, Cedar/Red Tree 0055156
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Tree, Cottonwood Tree 0055010
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Tree, Douglas Fir IgE 2003216
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Tree, Elm Tree 0055042
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Tree, Eucalyptus Tree 0055098
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Tree, Groundsel IgE 0098871
Method: Quantitative Enzyme Immunoassay

Allergen, Tree, Hackberry IgE 2007617
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Tree, Hazelnut IgE 0093506
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Tree, Hickory Shagbark IgE 0097934
Method: Quantitative Enzyme Immunoassay

Allergen, Tree, Italian Cypress IgE 0098867
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Tree, Japanese Cedar Tree 0055187
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Tree, Maple Sugar IgE 2007773
Method: Quantitative Enzyme Immunoassay

Allergen, Tree, Melaleuca Tree IgE 0098863
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Tree, Mesquite Tree 0055140
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Tree, Mountain Cedar (Juniper) Tree 0055007
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Tree, Mulberry Red IgE 0093504
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Tree, Oak Red IgE 0097933
Method: Quantitative Radioimmunoassay

Allergen, Tree, Oak Tree 0055045
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Tree, Olive Tree 0055155
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Tree, Palm/Queen Tree IgE 0098861
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Tree, Pecan (White Hickory) Tree 0055145
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Tree, Pine/Australian Tree 0055089
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Tree, Poplar White IgE 0098859
Method: Quantitative Enzyme Immunoassay

Allergen, Tree, Privet Tree 0055152
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Tree, Sweet Gum Tree 0055380
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Tree, Sycamore Tree 0055090
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Tree, Virginia Live Oak Tree 0055449
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Tree, Walnut Tree 0055093
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Tree, White Ash Tree 0055073
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Tree, White Mulberry Tree 0099554
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Tree, White Pine Tree 0055082
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Tree, Willow Tree 0055083
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Weed Allergens

Allergen, Weed, Careless Weed IgE 2007898
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Weed, Cocklebur 0099472
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Weed, Common/Short Ragweed 0055085
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Weed, Dandelion 0055086
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Weed, Dog Fennel IgE 2010830
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Weed, English Plantain 0055049
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Weed, False Ragweed 0055014
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Weed, Giant Ragweed 0055084
Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay

Allergen, Weed, Goldenrod 0098471
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Weed, Kochia/Firebush 0055018
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Weed, Lamb's Quarters 0055160
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Weed, Marsh Elder 0050910
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Weed, Mugwort 0055021
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Weed, Nettle 0099775
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Weed, Pigweed 0055025
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Weed, Sunflower Pollen IgE 0055185
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Weed, Wall pellitory (P. officinalis) 2006021
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Weed, Western Waterhemp (Amaranthus spp.) IgE 2008595
Method: Quantitative Enzyme Immunoassay

Allergen, Weed, Yellow Dock (Rumex crispus) IgE 0098433
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Guidelines

General References

Ahmad N, Zacharek MA. Allergic rhinitis and rhinosinusitis. Otolaryngol Clin North Am. 2008; 41(2): 267-81, v. PubMed

Dykewicz MS, Hamilos DL. Rhinitis and sinusitis. J Allergy Clin Immunol. 2010; 125(2 Suppl 2): S103-15. PubMed

Franzese CB, Burkhalter NW. The patient with allergies. Med Clin North Am. 2010; 94(5): 891-902. PubMed

Frew AJ. Allergen immunotherapy. J Allergy Clin Immunol. 2010; 125(2 Suppl 2): S306-13. PubMed

Fujimura T, Okamoto Y. Antigen-specific immunotherapy against allergic rhinitis: the state of the art. Allergol Int. 2010; 59(1): 21-31. PubMed

Gould HJ, Sutton BJ. IgE in allergy and asthma today Nat Rev Immunol. 2008; 8(3): 205-17. PubMed

Siles RI, Hsieh FH. Allergy blood testing: A practical guide for clinicians. Cleve Clin J Med. 2011; 78(9): 585-92. PubMed

WHO Collaborating Center for Asthma and Rhinitis, Bousquet J, Anto JM, Demoly P, Schünemann HJ, Togias A, Akdis M, Auffray C, Bachert C, Bieber T, Bousquet PJ, Carlsen KH, Casale TB, Cruz AA, Keil T, Carlsen KC Lodrup, Maurer M, Ohta K, Papadopoulos NG, Rodriguez R, Samolinski B, Agache I, Andrianarisoa A, Ang CS, Annesi-Maesano I, Ballester F, Baena-Cagnani CE, Basagaña X, Bateman ED, Bel EH, Bedbrook A, Beghé B, Beji M, Ben Kheder A, Benet M, Bennoor KS, Bergmann KC, Berrissoul F, Jensen B, Bleecker ER, Bonini S, Boner AL, Boulet LP, Brightling CE, Brozek JL, Bush A, Busse WW, Camargos PA M, Canonica GW, Carr W, Cesario A, Chen YZ, Chiriac AM, Costa DJ, Cox L, Custovic A, Dahl R, Darsow U, Didi T, Dolen WK, Douagui H, Dubakiene R, El-Meziane A, Fonseca JA, Fokkens WJ, Fthenou E, Gamkrelidze A, Garcia-Aymerich J, van Wijk G, Gimeno-Santos E, Guerra S, Haahtela T, Haddad H, Hellings PW, Hellquist-Dahl B, Hohmann C, Howarth P, Hourihane JO, Humbert M, Jacquemin B, Just J, Kalayci O, Kaliner MA, Kauffmann F, Kerkhof M, Khayat G, N'Goran K, Kogevinas M, Koppelman GH, Kowalski ML, Kull I, Kuna P, Larenas D, Lavi I, Le LT, Lieberman P, Lipworth B, Mahboub B, Makela MJ, Martin F, Martinez FD, Marshall GD, Mazon A, Melen E, Meltzer EO, Mihaltan F, Mohammad Y, Mohammadi A, Momas I, Morais-Almeida M, Mullol J, Muraro A, Naclerio R, Nafti S, Namazova-Baranova L, Nawijn MC, Nyembue TD, Oddie S, O'Hehir RE, Okamoto Y, Orru MP, Ozdemir C, Ouedraogo GS, Palkonen S, Panzner P, Passalacqua G, Pawankar R, Pigearias B, Pin I, Pinart M, Pison C, Popov TA, Porta D, Postma DS, Price D, Rabe KF, Ratomaharo J, Reitamo S, Rezagui D, Ring J, Roberts R, Roca J, Rogala B, Romano A, Rosado-Pinto J, Ryan D, Sanchez-Borges M, Scadding GK, Sheikh A, Simons FE R, Siroux V, Schmid-Grendelmeier PD, Smit HA, Sooronbaev T, Stein RT, Sterk PJ, Sunyer J, Terreehorst I, Toskala E, Tremblay Y, Valenta R, Valeyre D, Vandenplas O, van Weel C, Vassilaki M, Varraso R, Viegi G, Wang DY, Wickman M, Williams D, Wöhrl S, Wright J, Yorgancioglu A, Yusuf OM, Zar HJ, Zernotti ME, Zidarn M, Zhong N, Zuberbier T. Severe chronic allergic (and related) diseases: a uniform approach--a MeDALL--GA2LEN--ARIA position paper. Int Arch Allergy Immunol. 2012; 158(3): 216-31. PubMed

Williams P, Sewell WA C, Bunn C, Pumphrey R, Read G, Jolles S. Clinical immunology review series: an approach to the use of the immunology laboratory in the diagnosis of clinical allergy. Clin Exp Immunol. 2008; 153(1): 10-8. PubMed

References from the ARUP Institute for Clinical and Experimental Pathology®

Ravkov EV, Pavlov IY, Martins TB, Gleich GJ, Wagner LA, Hill HR, Delgado JC. Identification and validation of shrimp-tropomyosin specific CD4 T cell epitopes. Hum Immunol. 2013; 74(12): 1542-9. PubMed

Wang S, Delgado JC, Ravkov E, Eckels DD, Georgelas A, Pavlov IY, Cusick M, Sebastian K, Gleich GJ, Wagner LA. Penaeus monodon tropomyosin induces CD4 T-cell proliferation in shrimp-allergic patients. Hum Immunol. 2012; 73(4): 426-31. PubMed

Medical Reviewers

Last Update: April 2016