Ordering Recommendation

Not a first-line test in the evaluation of growth disorders. Aids in workup of suspected anterior hypopituitarism.

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation
Collect

Serum separator tube. Also acceptable: Green (sodium heparin).

Specimen Preparation

Transfer 0.5 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.3 mL)

Storage/Transport Temperature

Frozen.

Unacceptable Conditions

Tissue or urine. Grossly hemolyzed or lipemic specimens.

Remarks
Stability

After separation from cells: Ambient: 24 hours; Refrigerated: 1 week; Frozen: 1 year

Methodology

Quantitative Chemiluminescent Immunoassay

Performed

Sun-Sat

Reported

1-2 days

Reference Interval

Test Number
Components
Reference Interval
  IGF Binding Protein 3
Age
Male (ng/mL)
Female (ng/mL)
0-12 months 1039-3169 1039-3169
1-3 years 972-4123 1590-4225
4-5 years 1843-4968 2169-4790
6-7 years 1838-4968 2188-4996
8-9 years 1932-5858 2072-5504
10-11 years 1828-6592 2456-6992
12-13 years 2134-6598 2838-6846
14-15 years 2330-6550 2654-6680
16-17 years 2380-6400 2756-6908
18-19 years 2340-6632 2700-6492
20-24 years 2404-5948 3032-5992
25-29 years 2614-5792 2926-5858
30-34 years 2500-5806 2878-6650
35-39 years 2474-5208 2786-6084
40-44 years 2360-5560 2514-6014
45-49 years 2314-5700 2838-4954
50-54 years 2528-5050 2562-5596
55-59 years 2482-5460 2574-5914
60-64 years 2592-4770 2684-5130
65 years and older 2698-5680 2462-5274
Tanner Stage I 1878-6190 2314-6086
Tanner Stage II 2112-6208 2732-6738
Tanner Stage III 2372-6602 2870-7068
Tanner Stage IV & V 2336-6414 2756-7232

Interpretive Data



Compliance Category

FDA

Note

Hotline History

N/A

CPT Codes

82397

Components

Component Test Code* Component Chart Name LOINC
0070060 IGF Binding Protein 3 2483-6
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • IGF Binding Protein-3
  • IGFBP-3
  • IGFBP3
  • Insulin-Like Growth Factor Binding Protein-3
  • Somatomedin C binding protein
Insulin-Like Growth Factor Binding Protein-3 (IGFBP-3)