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Prostate Specific Antigen, Total
Ordering Recommendation
Preferred initial screening test for prostate cancer in conjunction with digital rectal exam. Use to monitor patients for recurrence of cancer.
New York DOH Approval Status
Specimen Required
Serum Separator Tube (SST). Also acceptable: Green (lithium heparin), Lavender (K2EDTA), or Pink (K2EDTA).
Allow specimen to clot completely at room temperature. Separate from cells ASAP or within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.5 mL)
Frozen.
Grossly hemolyzed specimens. Vaginal washings.
After separation from cells: Ambient: 24 hours; Refrigerated: 5 days; Frozen: 6 months
Methodology
Quantitative Electrochemiluminescent Immunoassay
Performed
Sun-Sat
Reported
Within 24 hours
Reference Interval
0.0-4.0 ng/mL
Interpretive Data
The Roche PSA electrochemiluminescent immunoassay is used. Results obtained with different test methods or kits cannot be used interchangeably. The Roche PSA method is approved for use as an aid in the detection of prostate cancer when used in conjunction with a digital rectal exam in individuals with a prostate age 50 years and older. The Roche PSA is also indicated for the serial measurement of PSA to aid in the prognosis and management of prostate cancer patients. Elevated PSA concentrations can only suggest the presence of prostate cancer until biopsy is performed. PSA concentrations can also be elevated in benign prostatic hyperplasia or inflammatory conditions of the prostate. PSA is generally not elevated in healthy individuals or Individuals with nonprostatic carcinoma.
FDA
Note
Hotline History
CPT Codes
84153
Components
| Component Test Code* | Component Chart Name | LOINC |
|---|---|---|
| 0070121 | Prostate Specific Antigen, Total | 83112-3 |
Aliases
- PSA
- SPSA
- Total PSA
