0070390
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Topiramate

TOPIR
Example Reports
Abnormal
Low
Normal

Ordering Recommendation

Optimize drug therapy and monitor patient adherence.

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation

Timing of specimen collection: Pre-dose (trough) draw - At steady state concentration.

Collect

Plain red. Also acceptable: Lavender (EDTA), pink (K2EDTA), or green (sodium or lithium heparin).

Specimen Preparation

Separate serum or plasma from cells ASAP or within 2 hours of collection. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.3 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Serum or plasma separator tubes.  Grossly hemolyzed specimens.

Remarks
Stability

After separation from cells: Ambient: 6 days; Refrigerated: 1 week; Frozen: 4 weeks

Methodology

Quantitative Enzyme Immunoassay

Performed

Sun-Sat

Reported

Within 24 hours

Reference Interval

Effective November 18, 2013

Therapeutic range:  5.0-20.0 µg/mL
Toxic:                Not well established

Interpretive Data

Pharmacokinetics varies widely, particularly with co-medications, age, and/or compromised renal function.  Adverse effects may include somnolence, fatigue, and dizziness.

Compliance Category

FDA

Note

Hotline History

N/A

CPT Codes

80201

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Components

Component Test Code* Component Chart Name LOINC
0070390 Topiramate 17713-9
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • tompamax concentration
  • tompamax level
  • Topamax
  • topiramate concentration
  • topiramate level
Topiramate