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(1,3)-Beta-D-Glucan (Fungitell)
Ordering Recommendation
Aid in the diagnosis of invasive/disseminated fungal infections (eg, P. jirovecii, Aspergillus, or Candida).
New York DOH Approval Status
Specimen Required
Plain Red or Serum Separator Tube (SST).
Separate from cells ASAP or within 2 hours of collection. Transfer 2 mL serum to a sterile ARUP Standard Transport Tube (ARUP supply # 43115) available online through eSupply using ARUP Connect ™ or contact ARUP Client Services at (800) 522-2787. (Min: 0.5 mL)
Refrigerated.
Specimen types other than those listed. Hemolyzed, icteric, or lipemic specimens.
Ambient: Unacceptable; Refrigerated: 2 weeks; Frozen: 2 weeks
Methodology
Semi-Quantitative Colorimetry
Performed
Mon-Fri
Reported
1-3 days
Reference Interval
Less than 31 pg/mL: Negative
31-59 pg/mL: Negative
60-79 pg/mL: Indeterminate
Greater than or equal to 80 pg/mL: Positive
Interpretive Data
The Fungitell test is indicated for presumptive diagnosis of fungal infection and should be used in conjunction with other diagnostic procedures. This test does not detect certain fungal species such as Cryptococcus, which produce very low levels of (1,3)-beta-D-glucan. This test will not detect the zygomycetes, such as Absidia, Mucor, and Rhizopus, which are not known to produce (1,3)-beta-D-glucan. In addition, the yeast phase of Blastomyces dermatitidis produces little (1,3)-beta-D-glucan and may not be detected by the assay.
FDA
Note
Reference ranges for pediatric patients (less than 18 years old) have not been established. Assay ranges were validated in adult subjects.
Hotline History
CPT Codes
87449
Components
| Component Test Code* | Component Chart Name | LOINC |
|---|---|---|
| 2002435 | (1,3)-beta-D-glucan Interpretation | 93479-4 |
| 2002436 | (1,3)-beta-D-glucan | 42176-8 |
Aliases
- Beta-D glucan
- Fungitell
- Glucan
