2004998
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Ganglioside (GM1, GD1b, and GQ1b) Antibodies, IgG and IgM

GM1 LIGHT
Example Reports
Negative
Positive

Ordering Recommendation

May have diagnostic relevance in multifocal motor neuropathy (MMN), Guillain-Barré syndrome (GBS), and Miller Fisher syndrome (MFS). For a more comprehensive ganglioside antibody panel when evaluating patients with autoimmune neuropathies, refer to Ganglioside (Asialo-GM1, GM1, GM2, GD1a, GD1b, and GQ1b) Antibodies (0051033). Test by itself is not diagnostic and should be used in conjunction with other clinical parameters to confirm disease.

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation
Collect

Serum separator tube.

Specimen Preparation

Transfer 0.3 mL serum to an ARUP Standard Transport Tube. (Min: 0.1 mL)

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

CSF, plasma, or other body fluids. Room temperature specimens. Contaminated, heat-inactivated, hemolyzed, severely icteric, or lipemic specimens.

Remarks
Stability

After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year.

Methodology

Semi-Quantitative Enzyme-Linked Immunosorbent Assay

Performed

Thu

Reported

1-8 days

Reference Interval

Test Number
 Components
 Reference Interval
  GM1 Antibody, IgG 50 IV or less
  GM1 Antibody, IgM 50 IV or less
  GD1b Antibody, IgG 0-50 IV
  GD1b Antibody, IgM 0-50 IV
  GQ1b Antibody, IgG 0-50 IV
  GQ1b Antibody, IgM 0-50 IV

Interpretive Data

Refer to report.

This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.


Component Interpretation
GM1 Antibody IgG 29 IV or less
30-50 IV
51-100 IV
101 IV or greater		 Negative
Equivocal
Positive
Strong positive
GM1 Antibody, IgM 29 IV or less
30-50 IV
51-100 IV
101 IV or greater		 Negative
Equivocal
Positive
Strong positive
GD1b Antibody, IgM 29 IV or less
30-50 IV
51-100 IV
101 IV or greater		 Negative
Equivocal
Positive
Strong positive
GD1b Antibody, IgG 29 IV or less
30-50 IV
51-100 IV
101 IV or greater		 Negative
Equivocal
Positive
Strong positive
GQ1b Antibody, IgG 29 IV or less
30-50 IV
51-100 IV
101 IV or greater		 Negative
Equivocal
Positive
Strong positive
GQ1b Antibody, IgM 29 IV or less
30-50 IV
51-100 IV
101 IV or greater		 Negative
Equivocal
Positive
Strong positive

Compliance Category

Laboratory Developed Test (LDT)

Note

Hotline History

N/A

CPT Codes

83516 x6

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Components

Component Test Code* Component Chart Name LOINC
0050582 GM1 Antibody, IgG 51729-2
0050584 GM1 Antibody, IgM 51703-7
2004999 GD1b Antibody, IgG 56541-6
2005000 GD1b Antibody, IgM 58977-0
2005001 GQ1b Antibody, IgG 57660-3
2005002 GQ1b Antibody, IgM 56545-7
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • Anti-GM Antibodies
  • Ganglioside Antibodies
  • Ganglioside (GM1) Antibodies, IgG and IgM
  • Ganglioside Abs IgG and IgM
  • GD1b IgG IgM
  • GM1, GD1b, GQ1b IgG and IgM
  • GQ1b IgG IgM
Ganglioside (GM1, GD1b, and GQ1b) Antibodies, IgG and IgM