2014704
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Maternal T Cell Engraftment in SCID, Maternal Specimen

SCID-MAT
Example Reports
See Note

Ordering Recommendation

Use to monitor engraftment of maternal T cells in patients with severe combined immunodeficiency (SCID) prior to allogenic stem cell transplantation.

New York DOH Approval Status

Testing is not New York state approved. Specimens from New York clients will be sent out to a New York state-approved laboratory.

Specimen Required

Patient Preparation
Collect

Lavender (EDTA), Pink (K2EDTA), or Yellow (ACD Solution A).
New York State Clients: Lavender (EDTA)

Specimen Preparation

Transport 2 mL whole blood. (Min: 1 mL)
New York State Clients: Transport 8 mL whole blood. (Min: 4 mL).

Storage/Transport Temperature

Refrigerated. Also acceptable: Ambient.

Unacceptable Conditions
Remarks
Stability

Room Temperature: 1 week; Refrigerated: 1 month; Frozen: unacceptable
New York State Clients: Room Temperature: 7 days; Refrigerated: 14 days; Frozen: Unacceptable

Methodology

Polymerase Chain Reaction (PCR)/Fragment Analysis

Performed

Sun-Sat

Reported

5-9 days

Reference Interval

Interpretive Data

Refer to report.

Compliance Category

Laboratory Developed Test (LDT)

Note

To complete Maternal T Cell Engraftment in SCID testing, samples should be collected to perform the following three tests: (1) A buccal  brush collected from the patient for Maternal T Cell Engraftment in SCID, Pre-Engraftment Specimen (ARUP test code 2014694), used as a genetic baseline for the patient. (2) A peripheral blood sample from the biological mother for Maternal T Cell Engraftment in SCID, Maternal Specimen (ARUP test code 2014704), used as a genetic baseline for the mother. (3) A peripheral blood sample collected from the patient for Maternal T Cell Engraftment in SCID (ARUP test code 2014699). T cells isolated from the blood sample will be genotyped for comparison to the patient and biological mother baseline genotypes. If T-cell sorting is not completed on the blood sample before submission of Maternal T Cell Engraftment in SCID (ARUP test code 2014699), BMT Cell Isolation (ARUP test code 2005498) will be added to each order of Maternal T Cell Engraftment in SCID (ARUP test code 2014699). Additional charges apply for cell isolation.

Hotline History

N/A

CPT Codes

See CPT code for Maternal T Cell Engraftment in SCID, Pre-Engraftment Specimen (ARUP test code 2014694)

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Components

Component Test Code* Component Chart Name LOINC
2014705 Maternal Specimen, Maternal Engraftment
2014706 Maternal Engraftment, Informative Loci
2014707 Maternal Engraftment, Mat Spec Interp
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • Maternal cell engraftment
  • Maternal engraftment
  • SCID
  • SCID engraftment
Maternal T Cell Engraftment in SCID, Maternal Specimen