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Time Sensitive

Ordering Recommendation

Aids in diagnosis, prognosis, and management of acute and chronic heart failure.

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation
Collect

Lavender (EDTA) or pink (K2EDTA).

Specimen Preparation

Separate plasma from cells within 2 hours of collection. Transfer 2 mL plasma to an ARUP Standard Transport Tube and freeze within 4 hours of collection. (Min: 0.5 mL)

Storage/Transport Temperature

Frozen.

Unacceptable Conditions

Frozen whole blood. Specimens collected in non-EDTA tubes. Specimens frozen in separator tube.  Specimen exposed to repeated freeze/thaw cycles. Refrigerated or room temperature specimens more than 4 hours old. Hemolyzed specimens.

Remarks
Stability

After separation from cells: Ambient: 4 hours; Refrigerated: 4 hours; Frozen: 4 months

Methodology

Quantitative Chemiluminescent Immunoassay

Performed

Sun-Sat

Reported

Within 24 hours

Reference Interval

Refer to Interpretive Data.

Interpretive Data

A cutoff of 100 pg/mL has been demonstrated to provide the maximal combination of sensitivity, specificity, and negative predictive value for contributing to the diagnosis of congestive heart failure (CHF).  A BNP value greater than 100 pg/mL is consistent with a diagnosis of CHF in the appropriate clinical setting. False-positive results are more common in females greater than 75 years of age.  Blood concentrations of natriuretic peptides may also be elevated in patients with myocardial infarction and in patients who are candidates for or are undergoing renal dialysis.

Compliance Category

FDA

Note

Hotline History

N/A

CPT Codes

83880

Components

Component Test Code* Component Chart Name LOINC
0030191 B-Type Natriuretic Peptide 30934-4
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • BNP
  • BNP (Brain Natriuretic Peptide)
  • Brain Natriuretic Peptide
  • Brain Type Natriuretic Peptide
  • Natriuretic Peptide
B-Type Natriuretic Peptide