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Recommendations when to order or not order the test. May include related or preferred tests.
May aid in the diagnosis of acute Epstein-Barr virus (EBV) infection and EBV reactivation in conjunction with other serologic studies. Molecular tests are preferred to detect EBV reactivation. Not a stand-alone test.
New York DOH Approval Status
Indicates test has been approved by the New York State Department of Health.
This test is New York state approved.
Specimen Required
Patient PreparationInstructions patient must follow before/during specimen collection.
CollectSpecimen type to collect. May include collection media, tubes, kits, etc.
Serum Separator Tube (SST).
Specimen PreparationInstructions for specimen prep before/after collection and prior to transport.
Allow specimen to clot completely at room temperature. Separate serum from cells ASAP or within 2 hours of collection. Transfer 2 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens.
Storage/Transport TemperaturePreferred temperatures for storage prior to and during shipping to ARUP. See Stability for additional info.
Refrigerated.
Unacceptable ConditionsCommon conditions under which a specimen will be rejected.
Contaminated, heat-inactivated or grossly hemolyzed specimens.
RemarksAdditional specimen collection, transport, or test submission information.
Label specimens plainly as "acute" or "convalescent."
StabilityAcceptable times/temperatures for specimens. Times include storage and transport time to ARUP.
After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)
Methodology
Process(es) used to perform the test.
Semi-Quantitative Chemiluminescent Immunoassay
Performed
Days of the week the test is performed.
Sun-Sat
Reported
Expected turnaround time for a result, beginning when ARUP has received the specimen.
1-2 days
Reference Interval
Normal range/expected value(s) for a specific disease state. May also include abnormal ranges.
Effective February 19, 2013
8.9 U/mL or less: Not Detected 9.0-10.9 U/mL: Indeterminate - Repeat testing in 10-14 days may be helpful. 11.0 U/mL or greater: Detected
Interpretive Data
May include disease information, patient result explanation, recommendations, or details of testing.
Compliance Category
FDA
Note
Additional information related to the test.
EBV EA-D values obtained with different manufacturers' assay methods may not be used interchangeably. The magnitude of the reported EBV EA-D level cannot be correlated to an endpoint titer.
Hotline History
N/A
CPT Codes
The American Medical Association Current Procedural Terminology (CPT) codes published in ARUP's Laboratory Test Directory are provided for informational purposes only. The codes reflect our interpretation of CPT coding requirements based upon AMA guidelines published annually. CPT codes are provided only as guidance to assist clients with billing. ARUP strongly recommends that clients confirm CPT codes with their Medicare administrative contractor, as requirements may differ. CPT coding is the sole responsibility of the billing party. ARUP Laboratories assumes no responsibility for billing errors due to reliance on the CPT codes published.
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
Aliases
Other names that describe the test. Synonyms.
EA-D IgG Ab
EAD Ab
EBNA Antibody
EBNA to EA-D
EBV Antibody to Early D Antigen
EBV Nuclear Antibody
Epstein-Barr Virus Antibody to Early D Antigen (EA-D), IgG
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