Ordering Recommendation

Mycoplasma pneumoniae Antibodies, IgG & IgM (0050399) is preferred.

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation
Collect

Serum separator tube.

Specimen Preparation

Separate serum from cells ASAP or within 2 hours of collection. Transfer 0.5 mL serum to an ARUP Standard Transport Tube. (Min: 0.1 mL) Parallel testing is preferred and convalescent specimens must  be received within 30 days from receipt of the acute specimens. Mark specimens plainly as "acute" or "convalescent."

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Bacterially contaminated, heat-inactivated, hemolyzed, icteric, lipemic, or turbid specimens.

Remarks
Stability

After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)

Methodology

Semi-Quantitative Enzyme-Linked Immunosorbent Assay

Performed

Sun-Sat

Reported

1-2 days

Reference Interval

< 0.10 U/L: Negative
0.10-0.32 U/L: Equivocal
> 0.32 U/L: Positive

Interpretive Data

Over 50 percent of healthy adults have a relatively high background of specific M. pneumoniae IgG antibodies in their sera, probably because of past M. pneumoniae infections. Therefore, paired sera obtained with a time interval of 1 to 3 weeks are highly recommended in adults to confirm reinfection by M. pneumoniae, which is demonstrated by a significant change in IgG antibodies. A significant change is indicated if one specimen is above 0.32 U/L and the other is below 0.20 U/L.

Compliance Category

FDA

Note

Hotline History

N/A

CPT Codes

86738

Components

Component Test Code* Component Chart Name LOINC
0050397 Mycoplasma Pneumoniae Antibody IgG 5255-5
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • M pneumoniae antibody IgG
  • M pneumoniae IgG
Mycoplasma pneumoniae Antibody, IgG