Ordering Recommendation

Aids in the diagnosis of infection with arboviruses.

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation
Collect

Serum separator tube. Also acceptable: Plain red.

Specimen Preparation

Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.5 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of acute specimens. Mark specimens plainly as "acute" or "convalescent."

Storage/Transport Temperature

Refrigerated.

Unacceptable Conditions

Contaminated, hemolyzed, or severely lipemic specimens.

Remarks
Stability

After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)

Methodology

Semi-Quantitative Indirect Fluorescent Antibody/Semi-Quantitative Enzyme-Linked Immunosorbent Assay

Performed

Tue, Fri

Reported

1-5 days

Reference Interval

Test Number
Components
Reference Interval
  St. Louis Encephalitis Ab, IgG, Serum Less than 1:16
  Calif Encephalitis Antibody IgG Less than 1:16
  Eastern Equine Enceph Ab, IgG Less than 1:16
  Western Equine Enceph Ab, IgG, Serum Less than 1:16
  West Nile Virus Ab, IgG, Ser 1.29 IV or less
  St. Louis Encephalitis Ab, IgM, Serum Less than 1:16
  California Encephalitis IgM Less than 1:16
  Eastern Equine Enceph Ab, IgM Less than 1:16
  Western Equine Enceph Ab, IgM, Ser Less than 1:16
  West Nile Virus Ab, IgM, Ser 0.89 IV or less

Interpretive Data

Refer to report.


Component Interpretation
West Nile Virus Antibody, IgG by ELISA, Serum 1.29 IV or less: Negative - No significant level of West Nile virus IgG antibody detected.
1.30-1.49 IV: Equivocal - Questionable presence of West Nile virus IgG antibody detected.  Repeat testing in 10-14 days may be helpful.
1.50 IV or greater: Positive - Presence of IgG antibody to West Nile virus detected, suggestive of current or past infection.
West Nile Virus Antibody, IgM by ELISA, Serum 0.89 IV or less: Negative - No significant level of West Nile virus IgM antibody detected.
0.90-1.10 IV: Equivocal - Questionable presence of West Nile virus IgM antibody detected.  Repeat testing in 10-14 days may be helpful.
1.11 IV or greater: Positive - Presence of IgM antibody to West Nile virus detected, suggestive of current or recent infection.

Compliance Category

FDA

Note

Hotline History

N/A

CPT Codes

86651 x2; 86652 x2; 86653 x2; 86654 x2; 86789; 86788

Components

Component Test Code* Component Chart Name LOINC
0050234 West Nile Virus Ab, IgG, Ser 38997-3
0050236 West Nile Virus Ab, IgM, Ser 38166-5
0050507 St. Louis Encephalitis Ab, IgG, Serum 10906-6
0050508 Calif Encephalitis Antibody IgG 10904-1
0050509 Eastern Equine Enceph Ab, IgG 10896-9
0050514 Western Equine Enceph Ab, IgG, Serum 6957-5
0098731 California Encephalitis IgM 10905-8
0098732 St. Louis Encephalitis Ab, IgM, Serum 10907-4
0098733 Eastern Equine Enceph Ab, IgM 10898-5
0098734 Western Equine Enceph Ab, IgM, Ser 6958-3
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • Arbovirus serology
  • California Encephalitis Antibody, IgG
  • California Encephalitis Antibody, IgM
  • Eastern Equine Encephalitis Antibody, IgG
  • Eastern Equine Encephalitis Antibody, IgM
  • Encephalitis Antibodies
  • St. Louis Encephalitis Antibody, IgG
  • St. Louis Encephalitis Antibody, IgM
  • West Nile Virus Antibody, IgG
  • West Nile Virus Antibody, IgM
  • Western Equine Encephalitis Antibody IgG
  • Western Equine Encephalitis, Antibody, IgM
Arbovirus Antibodies, IgG and IgM, Serum