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Recommendations when to order or not order the test. May include related or preferred tests.
Use with CA 125 to monitor ovarian cancer, usually epithelial subtype, post therapy if pretreatment level was elevated. Not recommended for monitoring known mucinous or germ cell ovarian cancer. Not a stand-alone test for ovarian cancer screening or diagnosis.
New York DOH Approval Status
Indicates test has been approved by the New York State Department of Health.
This test is New York state approved.
Specimen Required
Patient PreparationInstructions patient must follow before/during specimen collection.
CollectSpecimen type to collect. May include collection media, tubes, kits, etc.
Serum Separator Tube (SST). Also acceptable: Green (Lithium Heparin), Lavender (K2 EDTA), or Lavender (K3 EDTA).
Specimen PreparationInstructions for specimen prep before/after collection and prior to transport.
Allow specimen to clot completely at room temperature. Transfer 1 mL serum or plasma to an ARUP Standard Transport Tube. (Min: 0.5 mL)
Storage/Transport TemperaturePreferred temperatures for storage prior to and during shipping to ARUP. See Stability for additional info.
Frozen.
Unacceptable ConditionsCommon conditions under which a specimen will be rejected.
Grossly hemolyzed specimens.
RemarksAdditional specimen collection, transport, or test submission information.
StabilityAcceptable times/temperatures for specimens. Times include storage and transport time to ARUP.
Expected turnaround time for a result, beginning when ARUP has received the specimen.
Within 24 hours
Reference Interval
Normal range/expected value(s) for a specific disease state. May also include abnormal ranges.
0-140 pmol/L
Interpretive Data
May include disease information, patient result explanation, recommendations, or details of testing.
The Roche Human Epididymis Protein 4 (HE4) electrochemiluminescent immunoassay was used. Results obtained with different test methods or kits cannot be used interchangeably. The HE4 test is used as an aid in monitoring recurrence or progressive disease in patients with epithelial ovarian cancer. Serial testing for patient HE4 assay values should be used in conjunction with other clinical findings for monitoring ovarian cancer.
Compliance Category
FDA
Note
Additional information related to the test.
Hotline History
N/A
CPT Codes
The American Medical Association Current Procedural Terminology (CPT) codes published in ARUP's Laboratory Test Directory are provided for informational purposes only. The codes reflect our interpretation of CPT coding requirements based upon AMA guidelines published annually. CPT codes are provided only as guidance to assist clients with billing. ARUP strongly recommends that clients confirm CPT codes with their Medicare administrative contractor, as requirements may differ. CPT coding is the sole responsibility of the billing party. ARUP Laboratories assumes no responsibility for billing errors due to reliance on the CPT codes published.
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.
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