Ordering Recommendation

Essential first-line test for suspected acute porphyria in adults. Use in determining metabolic response to IV hematin.

New York DOH Approval Status

This test is New York state approved.

Specimen Required

Patient Preparation
Collect

Random urine.

Specimen Preparation

Protect from light. Transfer an 8 mL aliquot from a well-mixed collection to ARUP Amber Transport Tubes. (Min: 3.5 mL)

Storage/Transport Temperature

Frozen.

Unacceptable Conditions

Body fluids other than urine.

Remarks
Stability

Ambient: Unacceptable; Refrigerated: 4 days; Frozen: 1 month

Methodology

Quantitative Ion Exchange Chromatography/Spectrophotometry

Performed

Mon-Fri

Reported

1-4 days

Reference Interval

Components
Reference Interval
Porphobilinogen (PBG), Urine-per volume 0.0-8.8 µmol/L
Porphobilinogen, Rndm Urn-ratio to CRT No reference interval (mg/g crt)

Interpretive Data

This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes.

Compliance Category

Laboratory Developed Test (LDT)

Note

Appropriate test to rule out acute intermittent porphyria (AIP) and other acute attacks of other types of porphyrias associated with neurologic and/or psychiatric symptoms.

Hotline History

N/A

CPT Codes

84110

Components

Component Test Code* Component Chart Name LOINC
0020207 Creatinine, Urine - per volume 2161-8
0080262 Porphobilinogen (PBG), Urine -per volume 2811-8
2011477 Porphobilinogen, Rndm Urn-ratio to CRT 13797-6
* Component test codes cannot be used to order tests. The information provided here is not sufficient for interface builds; for a complete test mix, please click the sidebar link to access the Interface Map.

Aliases

  • PBG, Quantitative
  • Porphobilinogen
  • Watson-Schwartz Test
Porphobilinogen (PBG), Random Urine(Change effective as of 05/20/24: Refer to 0080260 in the May Hotline)