Free PSA

Content Review: November 2022 Last Update:
About This Topic

Do not use for initial prostate cancer screening. Prostate Specific Antigen, Free Percentage (Includes Free PSA and Total PSA) (0080206) should be considered as a secondary test to potentially determine the need for biopsy after an initial abnormal PSA screening result.

Recommendation

Prostate Specific Antigen, Total (0070121) is the test of choice for initial prostate cancer screening, with digital rectal exam (DRE) considered as a complementary baseline test.

Consider Prostate Specific Antigen Total with Reflex to Free PSA (0080264) as an alternative testing strategy.