In North America, ticks are primary vectors of infectious diseases, the most common of which is Lyme disease. Laboratory testing for Lyme disease is not required when tick exposure is plausible and erythema migrans (EM) rash, a distinguishing feature of Borrelia burgdorferi infection, is present. However, two-tiered serologic testing is recommended to support diagnosis in individuals with specific neurologic symptoms or atypical manifestations of Lyme disease.
Refer to ARUP Laboratories’ test offerings below.
ARUP Laboratory Tests
Modified Two-Tiered Testing
Semiquantitative Enzyme-Linked Immunosorbent Assay
Standard Two-Tiered Testing
Semi-Quantitative Enzyme-Linked Immunosorbent Assay/Qualitative Immunoblot