Microcytic Anemia Testing Algorithm

Microcytic anemia refers to any anemia in which the mean corpuscular volume (MCV) of red blood cells (RBCs) is low. Microcytic anemia may result from several different etiologies, including iron deficiency anemia, thalassemia, or anemia of chronic disease/inflammation. The workup for microcytic anemia includes a peripheral smear, typically followed by evaluation of iron stores.