Paraneoplastic neurologic syndromes (PNSs) are diseases that occur due to the remote effects of tumors (usually malignant), and include small cell lung cancer (SCLC), thymoma, neuroblastoma, ovarian, breast, testicular, and Hodgkin lymphoma. PNS may be suspected if neurologic disease is present, whether there is evidence of malignancy or not. An initial workup includes evaluating for infection and metabolic abnormalities; if neither are present, antibody testing may be considered.
See ARUP Lab Tests below.
ARUP Lab Tests
Quantitative Radioimmunoassay/Qualitative Radiobinding Assay/Semi-Quantitative Flow Cytometry/Semi-Quantitative Indirect Fluorescent Antibody
Semi-Quantitative Cell-Based Indirect Fluorescent Antibody/Qualitative Immunoblot/Quantitative Radioimmunoassay/Semi-Quantitative Enzyme-Linked Immunosorbent Assay
Semi-Quantitative Cell-Based Indirect Fluorescent Antibody/Quantitative Radioimmunoassay/Semi-Quantitative Enzyme-Linked Immunosorbent Assay