Vasculitis in Children Testing Algorithm

Testing for vasculitis in children is indicated in patients experiencing unexplained systemic illness with organ involvement in the renal, pulmonary, dermatologic, rheumatologic, or neurologic systems. Other testing may be warranted to rule out drug exposure, neoplasms, infection, and autoimmune disease. An initial workup for vasculitis in children includes urinalysis, C-reactive protein (CRP) or sedimentation rate (ESR), imaging, and biopsy.