Adult Transgender Laboratory Testing

Transgender individuals are those who do not identify with the sex they were assigned at birth. This discordance is called gender dysphoria or gender incongruence. A transgender male (previously referred to as female to male [FTM]) is someone who was assigned female at birth but who identifies and lives as a male. A transgender female (previously referred to as male to female [MTF]) is someone who was assigned male at birth but who identifies and lives as a female. Some, but not all, transgender individuals seek gender-affirming interventions up to and including gender reassignment surgery. This transgender terminology applies regardless of treatment or surgery decisions.

Gender affirmation often includes hormone therapy to help realign physical characteristics with gender identity. Laboratory testing plays an important role in establishing a safe and effective hormone regimen. Other medical care, including preventive care screening, should be personalized based on each patient’s unique biology and preferences. Data in this field are limited; much of the information provided below is summarized from the Endocrine Society guideline. For recommendations that are more detailed, refer to the Endocrine Society Clinical Practice Guideline on Endocrine Treatment of Gender-Dysphoric/Gender-Incongruent Persons. 

Tabs Content
Content Review: 
March 2019

Last Update: July 2019