Cold Agglutinin Disease

Cold agglutinin disease is a form of autoimmune hemolytic anemia caused by cold-reacting antibodies and classified as either primary (idiopathic) or secondary (due to an underlying disease). Laboratory testing generally includes CBC and an antiglobulin test (direct Coombs) to determine the presence of immunoglobulins and complement degradation products.  

Tabs Content

Last Update: July 2018