Granulomatosis with Polyangiitis - GPA

Granulomatosis with polyangiitis (GPA) is an antineutrophil cystoplasmic antibody (ANCA)-associated disorder characterized by vasculitis of small- to medium-sized blood vessels and necrotizing granulomatous inflammation in the upper and lower respiratory tract (Chapel Hill, 2012). GPA, formerly known as Wegener granulomatosis, classically involves a triad of organ systems, including the upper respiratory tract, lungs, and kidneys. However, GPA confined to the head and neck is not uncommon.

Tabs Content
Content Review: 
April 2018

Last Update: November 2019