Human chorionic gonadotropin (hCG) is produced at elevated levels during pregnancy as well as in gestational trophoblastic disease and due to some germ cell tumors. Additionally, hCG concentrations of a pituitary origin are sometimes detected in peri- and postmenopausal women.
Many female patients are tested for hCG before medical procedures or administration of medication that may harm a fetus. The interpretation of low-level hCG elevation in these females is problematic; such elevations might be benign or might represent malignancies such as gestational trophoblastic disease.
ARUP Laboratory Tests
Measures intact human chorionic gonadotropin (hCG) and free β subunit (hCGβ)
For tumor marker testing, order the beta-hCG quantitative test for tumor markers
Results obtained with different test methods or kits cannot be used interchangeably
Quantitative Electrochemiluminescent Immunoassay
Fournier T, Guibourdenche J, Evain-Brion D. Review: hCGs: different sources of production, different glycoforms and functions. Placenta. 2015;36 Suppl 1:S60-S65.