Sézary Syndrome

Sézary syndrome is an aggressive variant of cutaneous T-cell lymphoma that presents with an erythrodermic rash, and is characterized by a malignant T-cell clone in the skin and peripheral blood. Diagnosis depends on skin biopsy with lab testing to confirm clonality in blood is consistent with clonality in skin. Staging, prognosis, treatment decisions, and monitoring are largely based on clinical evaluation of skin, blood, visceral organ, and lymph node involvement.

Tabs Content
Content Review: 
February 2018

Last Update: October 2019