Food Allergies

  • Diagnosis
  • Background
  • Lab Tests
  • References
  • Related Topics

Indications for Testing

  • Medical history (pruritus, urticaria, gastrointestinal symptoms, angioedema anaphylaxis) indicating temporal association between food ingestion and symptoms (<2 hours), chronic diarrhea, and failure to thrive in children

Laboratory Testing

  • Two tests
    • Skin testing (pin prick) is no longer necessary, although generally less costly
    • Specific food serum IgE testing along with appropriate history – group or panel allergen tests may be helpful (ImmunoCAP appears to be best validated)
    • Neither test predicts severity of allergic reaction
    • Positive results may not be diagnostic – cross reactivity exists between proteins
    • Serum tryptase – elevated at 1-4 hours after anaphylaxis and can help confirm diagnosis
  • IgG testing is controversial
  • Food challenges
    • Should be performed as double-blind, placebo-controlled challenge
      • Must be done where resources are available to manage allergic reactions
    • Food challenges may be helpful but should not precede IgE testing
      • Administration of suspected food in gradually increasing doses
      • May be necessary if pin prick or IgE testing is negative and strong suspicion still exists for allergy
    • May be dangerous to do food testing in certain patients with severe allergies
      • Should wait at least 2 years after a severe reaction to perform testing
  • Patch testing – typically used in non-IgE mediated food allergy (eg, eosinophilic esophagitis)
    • No standard reagent methods or interpretation available
    • Not recommended by the National Institute of Allergy and Infectious Diseases for routine evaluation

Differential Diagnosis

The National Institute of Allergy and Infectious Diseases defines food allergy as an adverse immune response occurring reproducibly on exposure to a given food and is distinct from other adverse responses to food, such as food intolerance, pharmacologic reactions, and toxin-induced reactions..

Epidemiology

  • Incidence
    • Varies by geographic region
    • Increased incidence reported over the past 10 years – especially peanut allergies
  • Age
    • Adults – <3% have food allergies
    • Children – up to 6% of children <3 years are affected; ~4% worldwide
  • Sex
    • M:F, equal

Risk Factors

  • History of asthma
  • Parent or sibling with a history of atopy, asthma, or food allergy

Pathophysiology

  • Any food can potentially sensitize the immune system and cause antibody production
    • Foods most likely to cause sensitivity include those that are
      • Water soluble
      • Heat resistant
      • Acidic
      • Proteolytic
  • Most food allergies are IgE mediated – may also be IgG mediated
    • 90% of IgE-mediated allergies are caused by cow milk, soy, chicken eggs, peanuts, tree nuts, wheat, fish, and crustaceans
    • Non-IgE-mediated reactions are also common to soy, wheat, and cow milk
  • Wheat, milk, egg, and soy allergies usually disappear gradually with age
  • Food intolerance does not equal food allergy

Clinical Presentation

  • Classic IgE-mediated (immediate hypersensitivity)
    • Reaction occurs within 1-2 hours after food is ingested
    • Classification
      • Oral allergy syndrome – pruritus, tingling, swelling of lips and palate after fresh fruit/vegetable
        • Birch sensitivity – symptoms with raw carrots, celery, and apples
        • Ragweed sensitivity – symptoms with cantaloupe, watermelon, honeydew, and bananas
        • No symptoms when food is cooked
      • Gastrointestinal – nausea, abdominal pain, cramps, vomiting, diarrhea
      • Cutaneous – urticaria, angioedema, generalized pruritus, flushing, morbilliform rash
      • Respiratory – pruritus, tearing, nasal congestion, rhinorrhea, throat tightness, hoarseness, shortness of breath, dyspnea, wheezing
      • Cardiovascular – syncope, chest pain, arrhythmias, hypotension, shock
      • Neurologic – anxiety, headache, seizure, loss of consciousness
  • Mixed IgE/non-IgE
  • Non-IgE (cell-mediated)
    • Occurs ≥24 hours after food ingested
  • 80-85% of children outgrow food allergies by 5 years
  • Most persistent allergens are nuts, seeds, fish
    • Classification
      • Food protein-induced proctocolitis
        • Infants appear healthy
        • Blood-tinged stools in first 2-4 months of life
        • Usually secondary to milk or soy protein and most often in breast-fed infants
      • Food protein-induced enterocolitis syndrome
        • Infants appear ill
        • Bloody diarrhea, recurrent vomiting, failure to thrive
        • Most often secondary to milk and soy protein; rice, oat, other cereal grains, and chicken have also been implicated
        • Infants usually tolerate breast milk

Tests generally appear in the order most useful for common clinical situations. Click on number for test-specific information in the ARUP Laboratory Test Directory.

Allergens, Food, Common Adult Food IgE 0050486
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Limitations

Does not test for any other allergens

Follow Up

Individual allergen testing

Tryptase 0099173
Method: Quantitative Fluorescent Enzyme Immunoassay

Panels and Profiles

Allergens, Food, Cereal Profile 0055350
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergens, Food, Common Panel IgG 2007215
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergens, Food, Comprehensive Profile 1 0055100
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergens, Food, Extended Panel IgG 2007213
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergens, Food, Fish Profile IgE 2007036
Method: ImmunoCAP Fluorescent Enzyme Immunoassay

Allergens, Food, IgG Panel 2007216
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergens, Food, Meat Panel IgG 2007214
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergens, Food, Nut Mix Profile 0055345
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergens, Food, Nuts 0051831
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergens, Food, Profile 10 0055174
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergens, Food, Profile 13 0055301
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergens, Food, Profile 19 0055172
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergens, Food, Profile 4 0055142
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergens, Food, Profile 8 0055133
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergens, Food, Profile 9 0055104
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergens, Food, Salad Profile 0055340
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergens, Food, Seafood Profile 0055335
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergens, Food, Shell Fish Profile 0051835
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergens, Food, Southeast Profile 0055384
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergens, Food, Southwest Basic Profile 0055370
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergens, Food, Vegetable Profile IgE 0055330
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergens, Food, West Kentucky Group 0055218
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergens, Foods, Common 10 2002124
Method: ImmunoCAP Fluorescent Enzyme Immunoassay

Allergens, Inhalants/Foods, Comprehensive Profile 1 0055114
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergens, Inhalants/Foods, Comprehensive Profile 2 0055099
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergens, Inhalants/Foods, Environmental Profile 0055307
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergens, Inhalants/Foods, Pacific Northwest Profile 0055131
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergens, Inhalants/Foods, Profile A 0055126
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergens, Inhalants/Foods, Southeast Profile 0055240
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergens, Inhalants/Foods, Western Allergy Profile 0055129
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergens, Latex/Cross-Reactive Food Panel IgE 0055245
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergens, Pediatric Foods Profile 1 0055121
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergens, Pediatric Foods/Inhalants Profile 0055300
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Chronic Enteric Hypersensitivity Reflexive Profile 2010161
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay/Semi-Quantitative Enzyme-Linked Immunosorbent Assay

A-B

Allergen, Food, Almond 0099577
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Almond IgG 0090284
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Alpha-Gal (galactose-alpha-1,3-galactose) IgE 2007994
Method: Immunoassay

Allergen, Food, Alpha-Lactalbumin 0099543
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Anchovy IgE 0093498
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Annatto Seed IgE 2010720
Method: Quantitative Enzyme Immunoassay

Allergen, Food, Apple 0099632
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Apricot 0055423
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Artichoke IgE 2007179
Method: Quantitative Enzyme Immunoassay

Allergen, Food, Asparagus IgE 0098873
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Avocado 0099695
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Avocado IgG 2011723
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Baker's Yeast IgG 0097706
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Baker's Yeast/Brewer's Yeast 0055079
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Banana 0099634
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Banana IgG 0090286
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Barley 0055056
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Barley IgG 0097707
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Basil IgE 0093496
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Bass Black IgE 0099692
Method: Quantitative Enzyme Immunoassay

Allergen, Food, Bay Leaf IgE 0093494
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Beef 0055096
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Beef IgG 0097708
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Beet Root IgE 2006689
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Beta-Lactoglobulin 0055074
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Black Olive IgE 2010826
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Black Pepper 0055424
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Blackberry IgE 2007629
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Blue Mussel 0055425
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Blueberry 0055426
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Brazil Nut 0099574
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Broccoli 0098531
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Broccoli IgG 2011725
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Buckwheat IgE (Fagopyrum esculentum) 0092597
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

C-D

Allergen, Food, Cabbage 0055094
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Canola (Rapeseed) Oil IgE 2010834
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Caraway Seed IgE 2001903
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Carob Gum/Locust Bean IgE 2001907
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Carrot 0055005
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Casein 0055081
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Casein (Cow's Milk) IgG 0097653
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Cashew 0099573
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Cashew IgG 2011727
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Catfish IgE 0097629
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Cauliflower IgE 2010832
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Celery 0099054
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Cheddar Cheese IgG 2011817
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Cheese Mold 0099593
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Cheese Mold IgG 2011729
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Cheese, Cheddar 0099583
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Cherry IgE 0099466
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Chestnut 0055254
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Chicken 0055008
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Chicken IgG 0097656
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Chickpea (Garbanzo Bean) IgE 0055200
Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay

Allergen, Food, Chocolate 0099642
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Chocolate IgG 0097657
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Cinnamon 0098876
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Clam 0099488
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Clam IgG 2011731
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Clove IgE 0098875
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Coconut 0099473
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Coconut IgG 2011733
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Codfish IgE 0055036
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Coffee 0099757
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Coffee IgG 0097302
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Common Millet IgE 2010828
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Coriander/Cilantro IgE 2007623
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Corn 0055078
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Corn IgG 0097658
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Crab 0055011
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Crab IgG 2011735
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Cranberry IgE 0098874
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Crayfish IgE 0097637
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Cucumber IgE 0098868
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Cumin Seed IgE 2007780
Method: Quantitative Enzyme Immunoassay

Allergen, Food, Dill IgE 0093492
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

E-K

Allergen, Food, Egg White 0055013
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Egg White IgG 0097659
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Egg Whole 0055381
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Egg Yolk 0055212
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Egg Yolk IgG 0097315
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Eggplant 0055432
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Flaxseed/Linseed IgE 2003298
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Garlic 0099479
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Garlic IgG 0090287
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Ginger IgE 0098865
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Gluten 0099569
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Gluten IgG 0090289
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Goat Milk IgE 2007619
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Grape 0055015
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Grapefruit 0099641
Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay

Allergen, Food, Green Bean (String) IgE 0099649
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Guar Gum IgE 2001917
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Gulf Flounder IgE 0099739
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Haddock IgE 0098864
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Halibut 0098516
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Hazelnut (Filbert) 0098617
Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay

Allergen, Food, Herring IgE 0097631
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Honey IgE 2007615
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Honeydew Melon/Cantaloupe 0055435
Method: Quantitative ImmunoCAP® Fluorescent Enzyme Immunoassay

Allergen, Food, Hops 0055436
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Kidney Bean 0055440
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Kiwi 0055203
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergens, Food, Egg Components IgE 2013024
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

L-O

Allergen, Food, Lamb 0099631
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Lemon 0098270
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Lentil 0099659
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Lettuce 0055019
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Lettuce IgG 0097651
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Lima Bean/White Bean 0099766
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Lime IgE 0098271
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Lobster 0099062
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Lobster IgG 2011737
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Macadamia Nut IgE 0093246
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Mackerel 0098474
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Mahi Mahi IgE 2010732
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Malt 0099744
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Malt IgG 0097652
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Mandarin IgE 2010818
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Mango 0055204
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Milk (Cow's) 0055020
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Milk (Cows) Components IgE 2012146
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Milk (Sheep), IgE 2013375
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Mint IgE 2007613
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Mushroom 0099770
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Mushroom IgG 0097299
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Mustard 0055443
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Navy Bean 0055022
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Nectarine IgE 2010734
Method: Quantitative Enzyme Immunoassay

Allergen, Food, Nutmeg IgE 0093502
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Oat 0055040
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Oat IgG 0097654
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Olives IgG 2011815
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Onion 0099474
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Onion IgG 0097306
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Orange 0055023
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Orange IgG 0097647
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Orris Root IgE 0098862
Method: Quantitative Radioimmunoassay

Allergen, Food, Ovalbumin IgE 2006436
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Ovomucoid IgE 2006434
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Oyster 0099638
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Oyster IgG 2011739
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

P-R

Allergen, Food, Papaya 0055250
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Parsley 0099492
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Pea 0099895
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Peach 0099582
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Peanut 0055024
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Peanut Components IgE 2007211
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Peanut IgG 0097648
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Pear 0055207
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Pecan 0099572
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Pepper C. annuum IgE 0055002
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Pepper C. frutescens IgE 0055428
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Perch IgE 0099687
Method: Quantitative Enzyme Immunoassay

Allergen, Food, Pine (Pinon) Nut 0055445
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Pineapple 0099477
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Pineapple IgG 2011741
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Pistachio 0055447
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Plaice IgE 2008798
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Plum 0055448
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Poppy Seed IgE 0098858
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Pork 0099780
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Pork IgG 0097649
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Potato 0055051
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Potato (White) IgG 0097641
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Pumpkin IgE 2010824
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Quinoa IgE 2010820
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Raspberry IgE 0099493
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Red Snapper IgE 0097628
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Rice 0055054
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Rice IgG 0097323
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Rye 0055026
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Rye IgG 0097642
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

S-Z

Allergen, Food, Safflower IgE 2010738
Method: Quantitative Enzyme Immunoassay

Allergen, Food, Sage IgE 0093514
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Salmon 0099680
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Sardine IgE 0097638
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Scallop 0099495
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Scallop IgG 2011743
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Sesame Seed 0099698
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Shrimp 0055030
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Shrimp IgG 2011745
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Sole IgE 0093512
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Soybean 0055031
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Soybean IgG 0097643
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Spinach 0055208
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Squid IgE 0097632
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Strawberry 0099639
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Strawberry IgG 2011747
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Sugar Beet IgE 0098645
Method: Quantitative Enzyme Immunoassay

Allergen, Food, Sugar Cane IgE 0099736
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Sugar Cane IgG4 0097911
Method: Quantitative Enzyme Immunoassay

Allergen, Food, Summer Squash IgE 0099122
Method: Quantitative Enzyme Immunoassay

Allergen, Food, Sunflower Seed IgE 0099496
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Sweet Potato IgE 0097326
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Swordfish IgE 0097633
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Tea 0055451
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Thyme IgE 0093510
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Tilapia IgE 2003296
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Tomato 0055033
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Trout 0099727
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Tuna 0055062
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Tuna IgG 2011749
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Turkey 0099627
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Turkey IgG 2011751
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Turmeric IgE 2010742
Method: Quantitative Enzyme Immunoassay

Allergen, Food, Vanilla 0055452
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Walleye Pike IgE 2007611
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Walnut (Juglans spp.) IgE 0055209
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Walnut IgG 2011753
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Watermelon IgE 0055157
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Wheat 0055034
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Wheat IgG 0097636
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Whey IgE 0055453
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Whey IgG 0090291
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, White Pollock IgE 2010822
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Whitefish IgE 0097634
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Whole Egg, IgG 2011819
Method: Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay

Allergen, Food, Yam IgE 0097325
Method: Quantitative Enzyme Immunoassay

Allergen, Food, Zucchini IgE 0099134
Method: Quantitative Enzyme Immunoassay

Guidelines

Boyce JA, Assa'ad A, Burks W, Jones SM, Sampson HA, Wood RA, Plaut M, Cooper SF, Fenton MJ, Arshad H, Bahna SL, Beck LA, Byrd-Bredbenner C, Camargo CA, Eichenfield L, Furuta GT, Hanifin JM, Jones C, Kraft M, Levy BD, Lieberman P, Luccioli S, McCall KM, Schneider LC, Simon RA, Simons ER, Teach SJ, Yawn BP, Schwaninger JM, NIAID-Sponsored Expert Panel. Guidelines for the Diagnosis and Management of Food Allergy in the United States: Summary of the NIAID-Sponsored Expert Panel Report. J Allergy Clin Immunol. 2010; 126(6): 1105-18. PubMed

Burks W, Jones SM, Boyce JA, Sicherer SH, Wood RA, Assa'ad A, Sampson HA. NIAID-sponsored 2010 guidelines for managing food allergy: applications in the pediatric population. Pediatrics. 2011; 128(5): 955-65. PubMed

Chinthrajah RSharon, Tupa D, Prince BT, Block WMorgan, Rosa JSou, Singh AMarie, Nadeau K. Diagnosis of Food Allergy Pediatr Clin North Am. 2015; 62(6): 1393-408. PubMed

Eigenmann PA, Beyer K, Burks W, Lack G, Liacouras CA, Hourihane JO'B, Sampson HA, Sodergren E. New visions for food allergy: an iPAC summary and future trends. Pediatr Allergy Immunol. 2008; 19 Suppl 19: 26-39. PubMed

NIAID-Sponsored Expert Panel, Boyce JA, Assa'ad A, Burks W, Jones SM, Sampson HA, Wood RA, Plaut M, Cooper SF, Fenton MJ, Arshad H, Bahna SL, Beck LA, Byrd-Bredbenner C, Camargo CA, Eichenfield L, Furuta GT, Hanifin JM, Jones C, Kraft M, Levy BD, Lieberman P, Luccioli S, McCall KM, Schneider LC, Simon RA, Simons ER, Teach SJ, Yawn BP, Schwaninger JM. Guidelines for the diagnosis and management of food allergy in the United States: report of the NIAID-sponsored expert panel. J Allergy Clin Immunol. 2010; 126(6 Suppl): S1-58. PubMed

Patel BY, Volcheck GW. Food Allergy: Common Causes, Diagnosis, and Treatment Mayo Clin Proc. 2015; 90(10): 1411-9. PubMed

Sharma HP, Bansil S, Uygungil B. Signs and Symptoms of Food Allergy and Food-Induced Anaphylaxis Pediatr Clin North Am. 2015; 62(6): 1377-92. PubMed

Soares-Weiser K, Takwoingi Y, Panesar SS, Muraro A, Werfel T, Hoffmann-Sommergruber K, Roberts G, Halken S, Poulsen L, van Ree R, Vlieg-Boerstra BJ, Sheikh A, EAACI Food Allergy and Anaphylaxis Guidelines Group. The diagnosis of food allergy: a systematic review and meta-analysis. Allergy. 2014; 69(1): 76-86. PubMed

General References

Chafen JJ Schneide, Newberry SJ, Riedl MA, Bravata DM, Maglione M, Suttorp MJ, Sundaram V, Paige NM, Towfigh A, Hulley BJ, Shekelle PG. Diagnosing and managing common food allergies: a systematic review. JAMA. 2010; 303(18): 1848-56. PubMed

Eckman J, Saini SS, Hamilton RG. Diagnostic evaluation of food-related allergic diseases. Allergy Asthma Clin Immunol. 2009; 5(1): 2. PubMed

Gupta RS, Dyer AA, Jain N, Greenhawt MJ. Childhood food allergies: current diagnosis, treatment, and management strategies. Mayo Clin Proc. 2013; 88(5): 512-26. PubMed

Gómez E, Mayorga C, Gómez F, Blázquez ABelen, Díaz-Perales A, Blanca M, Torres MJosé. Food allergy: management, diagnosis and treatment strategies. Immunotherapy. 2013; 5(7): 755-68. PubMed

Järvinen KM, Sicherer SH. Diagnostic oral food challenges: procedures and biomarkers. J Immunol Methods. 2012; 383(1-2): 30-8. PubMed

Longo G, Berti I, Burks W, Krauss B, Barbi E. IgE-mediated food allergy in children. Lancet. 2013; 382(9905): 1656-64. PubMed

Sastre J. Molecular diagnosis in allergy. Clin Exp Allergy. 2010; 40(10): 1442-60. PubMed

Scarpellini E, Tack J. Food allergy: from diagnosis to treatment. Dig Dis. 2012; 30(2): 224-31. PubMed

Sicherer SH, Sampson HA. Food allergy: Epidemiology, pathogenesis, diagnosis, and treatment. J Allergy Clin Immunol. 2014; 133(2): 291-307; quiz 308. PubMed

Unsworth DJ, Lock RJ. Food allergy testing. Adv Clin Chem. 2014; 65: 173-98. PubMed

Medical Reviewers

Last Update: June 2016