Helicobacter pylori

Helicobacter pylori (H. pylori), previously known as Campylobacter pylori, is one of the most common bacterial pathogens in humans; over half of the world’s population is infected.  Approximately 35% of the U.S. population is infected,  with the highest prevalence in those with lower socioeconomic status, older age, and non-Caucasian ethnicity. Diagnostic testing can be divided into two categories: noninvasive (urea breath testing and stool antigen testing) and invasive (biopsy-based testing). For most patients with a low risk of gastric cancer, the test-and-treat strategy using noninvasive diagnostic testing is appropriate. In these cases, the choice of a urea breath test or stool antigen test can be based on availability, cost, and acceptability, as both options are highly sensitive and specific for detecting persistent H. pylori infection.  These same tests can also be used to evaluate the success of therapy.

Tabs Content
Content Review: 
May 2019

Last Update: May 2019