Myasthenia Gravis - MG

Myasthenia gravis (MG) is an autoimmune disease caused by antibodies to neuromuscular and intramuscular elements impairing function and leading to muscle weakness and fatigue. Traditionally, MG was defined by presence of antibodies that block or destroy receptors for the neurotransmitter acetylcholine. This definition has expanded to include the presence of other autoantibodies including muscle-specific kinase antibodies (MuSK) and lipoprotein receptor-related protein 4 (LRP4) antibodies. Identification of select autoantibodies may assist with treatment, prognosis, and diagnosis of thymoma. Some patients are seronegative.

Tabs Content
Content Review: 
September 2017

Last Update: December 2018