Systemic Sclerosis - Scleroderma

Systemic sclerosis, also called scleroderma, is a chronic, multisystem autoimmune disorder characterized by thickening of the skin and accumulation of connective tissue in various organs. Anti-Scl-70, anticentromere antibody (ACA), and anti-RNA polymerase III are considered criteria antibody tests for the workup of systemic sclerosis.

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Last Update: November 2018