Systemic Autoimmune Rheumatic Diseases – Connective Tissue Diseases

Systemic autoimmune rheumatic diseases (SARDs) are characterized by autoantibodies that may affect many tissues and organs throughout the body. Laboratory testing for antinuclear antibodies (ANA) and specific autoantibodies associated with the presence of ANA may be useful in the evaluation of these diseases. The SARDS include systemic lupus erythematosus (SLE), Sjögren syndrome, mixed connective tissue disease/undifferentiated connective tissue disease, systemic sclerosis (scleroderma), idiopathic inflammatory myopathies (including polymyositis, dermatomyositis, and necrotizing autoimmune), and overlap syndromes.

ANA and related autoantibodies may also be useful in evaluating autoimmune liver diseases such as autoimmune hepatitis and primary biliary cholangitis.

Tabs Content
Content Review: 
April 2018

Last Update: May 2018