Colorectal Cancer

Colorectal cancer (CRC) is the third most common form of cancer in the U.S. While sporadic colon cancers are more common, hereditary colon cancers are also frequent, and identification of these affects screening recommendations both for the individual and family members. CRC screening strategies rely on imaging, laboratory testing, or a combination of the two. No serum biomarkers have been validated for CRC diagnosis; however, monitoring of serum carcinoembryonic antigen (CEA) is recommended following resection of most CRCs to detect recurrence. Molecular testing of cancer tissue, including evaluation for microsatellite instability (MSI), is recommended to guide treatment decisions, especially in individuals at high risk for hereditary nonpolyposis colorectal cancer (HNPCC).

Tabs Content
Content Review: 
May 2018

Last Update: November 2019