Glucagonomas are a type of pancreatic neuroendocrine tumor (PNET) that produce excessive amounts of glucagon, which causes glucose intolerance, weight loss, and a distinctive rash (migratory necrolytic erythema). These tumors have a very high malignant potential and are the third most common functional PNET. They are rarely associated with genetic syndromes, in contrast to some other PNETs.

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Last Update: January 2020