Treponema pallidum - Syphilis

Treponema pallidum subspecies pallidum is the causative agent of venereal syphilis, a sexually transmitted infection (STI). If left untreated, syphilis can result in multisystem involvement with significant morbidity. Traditional serologic screening for syphilis initially uses nontreponemal testing, with confirmation of reactive results using a treponemal test. New reverse algorithms initially use treponemal testing (usually enzyme immunoassays [EIA] or chemiluminescence immunoassays [CIA]), with confirmation of reactive results using a nontreponemal test.

Tabs Content
Content Review: 
November 2017

Last Update: April 2018