Unstable Hemoglobinopathies

The unstable hemoglobinopathies are rare inherited hemoglobinopathies in which the solubility of hemoglobin is altered, often leading to hemoglobin precipitates (Heinz bodies), reduced red blood cell (RBC) lifespan, and hemolytic anemia. The clinical severity and presentation of the unstable hemoglobinopathies vary widely, and they are frequently underdiagnosed or misdiagnosed.  Laboratory testing for unstable hemoglobinopathies consists of an initial evaluation, specialized testing, and genetic testing.

Tabs Content
Content Review: 
August 2019

Last Update: December 2019