Hemolytic Anemias

Hemolytic anemias, which result from premature destruction of red blood cells (RBCs),  may be hereditary or acquired. Hemolytic anemias can be due to numerous causes, including RBC membrane disorders, RBC enzyme defects, immune conditions, hemoglobinopathies, and thrombotic microangiopathies, among other causes (see Classification section).  Common hemolytic anemias include glucose-6-phosphate dehydrogenase (G6PD) deficiency, pyruvate kinase (PK) deficiency, and hereditary spherocytosis. Laboratory testing includes an initial evaluation for hemolysis, secondary testing to determine the etiology of hemolytic anemia, and, in some cases, molecular testing to confirm the diagnosis or determine recurrence risk.

Tabs Content
Content Review: 
November 2019

Last Update: November 2019