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Autoimmune Hepatitis
Disease Topics — Autoimmune hepatitis (AIH) is a chronic autoimmune liver disease (ALD) that is characterized by hypergammaglobulinemia.  If diagnosed and treated promptly, patients can expect a normal or nearly nor
Viral Hepatitis
Disease Topics — Hepatitis, or inflammation of the liver, may be caused by viral infection. Hepatitis A, B, C, D, and E viruses (HAV, HBV, HCV, HDV, and HEV) infect hepatocytes and cause acute or chronic hepatitis.
Autoimmune Liver Disease Testing Algorithm
Algorithm — A patient may have symptoms of liver disease or hepatitis without a clear cause. If the patient has elevated transaminases but all viral serologies are negative, more testing is needed.
Evaluation of Liver Function
Disease Topics — There is a broad spectrum of laboratory tests used to evaluate liver function and liver damage. Colloquially, these are referred to as liver function tests, although they are not all direct measures of liver function.
Connective Tissue Diseases - Systemic Autoimmune Rheumatic Diseases
Disease Topics — Connective tissue or systemic autoimmune rheumatic diseases (SARDs) are characterized by autoantibodies that can affect tissues and organs throughout the body.
Primary Biliary Cholangitis - PBC
Disease Topics — Primary biliary cholangitis (PBC), previously referred to as primary biliary cirrhosis, is an autoimmune liver disorder characterized by chronic, progressive cholestatic disease.
Primary Sclerosing Cholangitis – PSC
Disease Topics — Primary sclerosing cholangitis (PSC) is a progressive autoimmune liver disease (ALD) that often leads to cirrhosis and may eventually require liver transplantation. 
Sjögren Syndrome
Disease Topics — Sjögren syndrome is an autoimmune disease characterized by lymphocytic infiltration of exocrine glands that results in dry eyes and dry mouth; other common symptoms include fatigue and joint pain.
Hemolytic Anemias
Disease Topics — Hemolytic anemias, which result from premature destruction of red blood cells (RBCs),  may be hereditary or acquired.
Hemophilia - Factor VIII or IX Deficiency
Disease Topics — Hemophilia A and hemophilia B are bleeding disorders caused by genetic variants in the F8 or F9 gene that result in deficiencies of factor VIII (FVIII) in hemophilia A or factor IX (FIX) in hemophilia B, respe