Human Immunodeficiency Virus 1, Antiretroviral Drug Resistance Testing - HIV Drug Resistance

Drug resistance develops to all classes of HIV antiretroviral drugs. The use of three or more highly active antiretroviral therapy (HAART) agents is used to counter this tendency. The U.S. Department of Health and Human Services (HHS) Guidelines for the Use of Antiretroviral Agents in HIV-1-Infected Adults and Adolescents lists recommendations for initiating drug regimens in antiretroviral-naive patients.  

Drug resistance testing is conducted before the start of therapy to assist with selection of optimal treatment regimens and again when treatment failures occur. Drug resistance variants can be detected using phenotypic and genotypic methods.

Tabs Content
Content Review: 
March 2017

Last Update: August 2019